We strive to fulfill the unmet 'wishes' that were just out of reach.
Our goal is to quickly deliver innovative treatments that address the unmet medical needs of patients. "Without limiting ourselves to any specific disease areas, we drive open-innovation drug discovery in small molecule and nucleic acid pharmaceuticals through collaboration with various research institutions."
Research and Development Structure
We have a fully integrated drug discovery function that enables a seamless process from project planning and research to approval application. By adding nucleic acid modalities (method and means) into our small-molecule drug discovery platform, we are enhancing our drug discovery capabilities. Our strength lies in our small, elite team with a wide range of expertise. Starting from the planning and research stage, the research staff maintain strong horizontal interconnections, and projects are advanced as a unified team where representatives from each phase gather for discussions. We work on strengthening "collaborative power, agility, and enthusiasm" across organizational barriers, leading to the early resolution of challenges in the drug discovery process.
Planning and Research
We are committed to capturing "genuine medical needs" through proactive information gathering and communication with healthcare professionals. The Research and Development Planning Department is responsible for the nucleic acid field, while the Open Innovation Department leads the planning and research into small molecules.
Exploratory Research and Optimization Research
We are dedicated to the formulation of concepts that meet medical needs, while ensuring tight-knit information sharing throughout the DMTA (Design/Make/Test/Analyze) cycle, which is essential for drug discovery. To meet the target product profile (TPP) of a new drug, we meticulously execute quality- and data-driven processes, aiming to acquire high-quality lead compounds (new drug candidates).
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Use of AI in Drug Discovery
We are utilizing "drug discovery AI" to enhance research efficiency and increase the probability of success. We are participating in the development of next-generation drug discovery AI (DAIIA) through industry-academia collaboration, leveraging its outcomes to develop new drugs.
We aim to increase the success rate of proof of concept (PoC) in clinical development by conducting translational research to verify efficacy and safety.
Clinical development
By forging relationships with medical institutions built on trust, we conduct ethically based high-quality clinical trials. With a patient-centered approach, our goal is to deliver new treatments as quickly as possible. Leveraging our expertise in designing efficient development packages and clinical trial plans that can be applied to a wide range of diseases, we are also taking on challenges in new therapeutic areas.
CMC (Chemistry, Manufacturing, and Controls)
CMC research involves active pharmaceutical ingredient (API) research, formulation research, quality assurance, and quality control, all of which are essential for the approval of new prescription drugs. We have established a CMC research facility at the Mie Research Park dedicated to pursuing "patient-centered formulation development" that prioritizes patient convenience throughout the research process.
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OSDrC® (One-Step Dry Coating) Technology
We are also actively engaged in "iku-yaku" (drug improvement). Our commitment to this approach has led to the development of OSDrC® (One-Step Dry-Coating) technology, which enables the creation of new formulations that were previously inconceivable with conventional formulation techniques.
Mie Research Park is a drug discovery research hub located in a lush green environment where approximately 100 research staff members are actively engaged in research. The Pharmaceutical Research Institute and the CMC Research Institute work seamlessly together, facilitating smooth progress in discovery research, optimization research, preclinical research, and CMC research. We are also taking on the challenge of planning and research aimed at the discovering new seeds.
Identify hit compounds rapidly from a vast library of compounds and create novel clinical compounds.
Collect the data necessary to transform clinical candidate compounds into medications.
Actively expand drug improvement (iku-yaku) activities, such as broadening the indications of existing products and conducting studies into their utility.
CMC Research Institute
Conduct comprehensive research on active pharmaceutical ingredient manufacturing methods, formulation design, and quality assessment to create high-quality prescription drugs.
Development and application of innovative formulation technology (OSDrC® Technology)
Utilization of formulation technology in the creation of prescription drugs
Contact Us
We always welcome proposals for joint research and drug discovery collaborations. Please feel free to contact us using the form below.
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