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Abstract 2000

 

Title A therapeutic drug for diabetic neuropathy : Aldose reductase inhibitor,Fidarestat.
Authors K Mizuno
Publication Cell (Tokyo), 32, 27-31 (2000)

Title Inhibitory effects of fidarestat on aldose reductase and aldehyde reductase activity evaluated by a new method using HPLC with post-column spectrophotometric detection
Authors K Mizuno,T Suzuki,T Tanaka,K Taniko,T Suzuki
Publication Biol Pharm Bull 2000 Feb;23(2):244-248

Title Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats
Authors N Kato,K Mizuno,M Makino,T Suzuki,S Yagihashi
Publication Diabetes Res Clin Pract (2000) 50: 77-85

Title A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]- 2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography
Authors M Oka,Y Matsumoto,S Sugiyama,N Tsuruta,M Matsushima
Publication J Med Chem 2000 Jun 15;43(12):2479-2483

Title 1-Bromopropane, an Alternative to Ozone Layer Depleting Solvents, Is Dose-Dependently Neurotoxic to Rats in Long-Term Inhalation Exposure
Authors G Ichihara, J Kitoh, Xiaozhong Yu, N Asaeda, H Iwai, T Kumazawa, E Shibata, T Yamada, Hailan Wang, Zhenlin Xie, Y Takeuchi
Publication Toxicological Sciences,2000,55:116-123

Title Reproductive Toxicity of 1-Bromopropane, a Newly Introduced Alternative to Ozone Layer Depleting Solvents, in Male Rats.
Authors Gaku Ichihara, Xiaozhong Yu, J Kitoh, N Asaeda, T Kumazawa, H Iwai, E Shibata, T Yamada, Hailan Wang, Zhenlin Xie, K Maeda, H Tsukamura, Y Takeuchi
Publication Toxicological Sciences,2000,54:416-423

Title In vitropharmacological profile of SK-896, a new human motilin analogue
Authors K Tsukamoto, N Kuboyama, M Yamano, T Nakazawa
Publication Pharmacology,2000,60:128-135

Title Atrophy of Rat Exorbital Lacrimal Glands Induced by Atropine
Authors Y Tagawa,H Iwai,T Kumazawa,K Haruyama,K Ichikawa ,S Fukushima
Publication J. Toxicologic Pathology,2000,13(1):7-11h

Title Comparison Among Three Loop Diuretics, Azosemide, Torasemide, and Furosemide on the Pattern of Diuretic Action in Rats.
Authors K Mizuno, S Yashima , Tjomori
Publication Japanese Pharmacology & Therapeutics,2000,28(2):123-132

Title Facilitaion of acetylcholine release by SK-951, a benzofuran derivative, via the 5-hydroxytryptamine4 Receptor in Guinea Pig Stomach
Authors M Takeda, K Tsukamoto, T Suzuki,Y Sakurai-Yamashita, K Taniyama
Publication Japanease Journal of Pharmacology,2000,82,:138-143

Title The effect of SK-896 on post-operative ileus in dogs: gastrointestinal motility pattern and transit
Authors K Tsukamoto, M Mizutani, M Yamano, Y Tagi, M Takeda
Publication European Journal of Pharmacology,2000,401:97-107

Title Effect of Anti-inflammatory Drug, Nabumetone on Rat Gastric Mucosa
Authors M Okamoto,S Yokochi,H Hashimoto,Y Ishiwata
Publication Japanese Pharmacology & Therapeutics, 2000; 28(12):1015-1018

Title Synthesis of 1-Azabicyclo[3.3.0]octane Derivatives and Their Effects as Piracetam-like Nootropics
Authors M Oka.,Y Matsumoto,K Hirooka.,T Suzuk
Publication Chem. Pharm. Bull.,2000,48:1121-1124

Title Effects of atropine sulfate on rat harderian glands: Correlation between morphological changes and porphyrinˇˇlevels.
Authors H Iwai,Y Tagawa, I Hayasaka, T Yanai, T Masegi
Publication J. Toxicol. Sci. 25, 151-159 (2000)

Title Pharmaceutical Properties of Jelly Dosage Form Containing Calcium Polystyrene Sulfonate
Authors M Ando, T Kouzaki, F Higuchi, T Ichihashi, M Takeda, Y Mizutani, H Uesaka
Publication J.Pharm.Sci.Technol.,Jpn.,60(4),261-270(2000)

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