Abstract 2000
| Title | A therapeutic drug for diabetic neuropathy : Aldose reductase inhibitor,Fidarestat. |
| Authors | K Mizuno |
| Publication | Cell (Tokyo), 32, 27-31 (2000) |
| Title | Inhibitory effects of fidarestat on aldose reductase and aldehyde reductase activity evaluated by a new method using HPLC with post-column spectrophotometric detection |
| Authors | K Mizuno,T Suzuki,T Tanaka,K Taniko,T Suzuki |
| Publication | Biol Pharm Bull 2000 Feb;23(2):244-248 |
| Title | Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats |
| Authors | N Kato,K Mizuno,M Makino,T Suzuki,S Yagihashi |
| Publication | Diabetes Res Clin Pract (2000) 50: 77-85 |
| Title | A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]- 2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography |
| Authors | M Oka,Y Matsumoto,S Sugiyama,N Tsuruta,M Matsushima |
| Publication | J Med Chem 2000 Jun 15;43(12):2479-2483 |
| Title | 1-Bromopropane, an Alternative to Ozone Layer Depleting Solvents, Is Dose-Dependently Neurotoxic to Rats in Long-Term Inhalation Exposure |
| Authors | G Ichihara, J Kitoh, Xiaozhong Yu, N Asaeda, H Iwai, T Kumazawa, E Shibata, T Yamada, Hailan Wang, Zhenlin Xie, Y Takeuchi |
| Publication | Toxicological Sciences,2000,55:116-123 |
| Title | Reproductive Toxicity of 1-Bromopropane, a Newly Introduced Alternative to Ozone Layer Depleting Solvents, in Male Rats. |
| Authors | Gaku Ichihara, Xiaozhong Yu, J Kitoh, N Asaeda, T Kumazawa, H Iwai, E Shibata, T Yamada, Hailan Wang, Zhenlin Xie, K Maeda, H Tsukamura, Y Takeuchi |
| Publication | Toxicological Sciences,2000,54:416-423 |
| Title | In vitropharmacological profile of SK-896, a new human motilin analogue |
| Authors | K Tsukamoto, N Kuboyama, M Yamano, T Nakazawa |
| Publication | Pharmacology,2000,60:128-135 |
| Title | Atrophy of Rat Exorbital Lacrimal Glands Induced by Atropine |
| Authors | Y Tagawa,H Iwai,T Kumazawa,K Haruyama,K Ichikawa ,S Fukushima |
| Publication | J. Toxicologic Pathology,2000,13(1):7-11h |
| Title | Comparison Among Three Loop Diuretics, Azosemide, Torasemide, and Furosemide on the Pattern of Diuretic Action in Rats. |
| Authors | K Mizuno, S Yashima , Tjomori |
| Publication | Japanese Pharmacology & Therapeutics,2000,28(2):123-132 |
| Title | Facilitaion of acetylcholine release by SK-951, a benzofuran derivative, via the 5-hydroxytryptamine4 Receptor in Guinea Pig Stomach |
| Authors | M Takeda, K Tsukamoto, T Suzuki,Y Sakurai-Yamashita, K Taniyama |
| Publication | Japanease Journal of Pharmacology,2000,82,:138-143 |
| Title | The effect of SK-896 on post-operative ileus in dogs: gastrointestinal motility pattern and transit |
| Authors | K Tsukamoto, M Mizutani, M Yamano, Y Tagi, M Takeda |
| Publication | European Journal of Pharmacology,2000,401:97-107 |
| Title | Effect of Anti-inflammatory Drug, Nabumetone on Rat Gastric Mucosa |
| Authors | M Okamoto,S Yokochi,H Hashimoto,Y Ishiwata |
| Publication | Japanese Pharmacology & Therapeutics, 2000; 28(12):1015-1018 |
| Title | Synthesis of 1-Azabicyclo[3.3.0]octane Derivatives and Their Effects as Piracetam-like Nootropics |
| Authors | M Oka.,Y Matsumoto,K Hirooka.,T Suzuk |
| Publication | Chem. Pharm. Bull.,2000,48:1121-1124 |
| Title | Effects of atropine sulfate on rat harderian glands: Correlation between morphological changes and porphyrinˇˇlevels. |
| Authors | H Iwai,Y Tagawa, I Hayasaka, T Yanai, T Masegi |
| Publication | J. Toxicol. Sci. 25, 151-159 (2000) |
| Title | Pharmaceutical Properties of Jelly Dosage Form Containing Calcium Polystyrene Sulfonate |
| Authors | M Ando, T Kouzaki, F Higuchi, T Ichihashi, M Takeda, Y Mizutani, H Uesaka |
| Publication | J.Pharm.Sci.Technol.,Jpn.,60(4),261-270(2000) |
